Immune adsorption / plasma exchange
differences
Immune adsorption:
Selective: removal of immunoglobulins;
Good removal of IgG, less good IgA and IgM
Return of the cleaned own plasma to the patient;
no foreign proteins necessary
Processing of large plasma volumes and high frequencies possible
Higher material costs, technically more complex, more time-consuming
Very rare side effects, well tolerated
Treatment duration significantly longer, calculated individually for each patient
Treated plasma amount up to 10 liters / day
Plasma exchange:
Not selective: removal of all plasma proteins
Good removal of IgG, IgA and IGM
Removal of small amounts of coagulation factors
Volume replacement solution:
(synthetic human albumin solution, if necessary FFP, no foreign blood)
Volumes and frequencies are limited
Lower material costs, less time consuming
Side effects from volume shifts are rare
Duration 2h + return time
Treated plasma amount approx. 2 liters / day